Using Network Alignment to serve the discovery of undealying disease

In the recent reports, the most question which was thrown to me is, what the hell of designing a network comparison algorithm can be used to? Now, Xuebing Wu et al. help me to give one answer: network alignment can be used to detect or predict the underlying disease families. (The other applications include reconstructing the phylogenetic relationships of organisms, integrating data of genome and proteome, querying the interested pathway within the known pathway databases, and so on.)

Here is the link of this paper: http://bioinformatics.oxfordjournals.org/cgi/content/short/25/1/98?. Thank Samuel for helping download it.